Toll-like receptor 4 in atherosclerosis

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Toll-like receptor 4 in atherosclerosis

Toll-like receptor 4 (TLR4) is key regulators of both innate and adaptive immune responses. TLR4 recognizes pathogen-associated molecular patterns (PAMPs) and activates the inflammatory cells. The function of TLR4 in atherosclerosis has been investigated in mouse knockout studies and epidemiological studies of human TLR4 polymorphisms. These studies have shown that TLR4 function affects the ini...

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ژورنال

عنوان ژورنال: Journal of Cellular and Molecular Medicine

سال: 2007

ISSN: 1582-1838,1582-4934

DOI: 10.1111/j.1582-4934.2007.00011.x